ADNCD
   
 
 
Select Mode of Action
Anti-diabetic mode of action: Insulin Sensitizers
Peroxisome Proliferator-Activated Receptor gamma, alpha and delta activators (PPAR- γ, α and δ activation)
S.No. Compound Reference Activated enzyme Physicochemical Properties and Toxicity Risks
1 Corosolic acidMiura et al., 2012PPAR- α Properties and Risk Assessment
2 PalmatineVasanthi and Kannan, 2012PPAR- α Properties and Risk Assessment
3 GeraniolKatsukawa et al., 2011PPAR- α Properties and Risk Assessment
4 CitronellolKatsukawa et al., 2011PPAR- α Properties and Risk Assessment
5 D-limoneneJing et al., 2013PPAR- α Properties and Risk Assessment
6 3-Caffeoylquinic AcidZhang et al., 2013PPAR- α Properties and Risk Assessment
7 PiperineKim et al., 2011PPAR- δ Properties and Risk Assessment
8 PipernonalineKim et al., 2011PPAR- δ Properties and Risk Assessment
9 DehydropipernonalineKim et al., 2011PPAR- δ Properties and Risk Assessment
10 Rosiglitazone(Known Drug)Liu et al., 2005PPAR- γ Properties and Risk Assessment
11 Troglitazone(Known Drug)Larsen et al., 2003PPAR- γ Properties and Risk Assessment
12 Corosolic acidMiura et al., 2012PPAR- γ Properties and Risk Assessment
13 RutinPetersen and Shulman, 2006PPAR- γ Properties and Risk Assessment
14 GlycyrinKuroda et al., 2003 Saxena, 2005PPAR- γ Properties and Risk Assessment
15 Amorfrutin 2Weidner et al., 2012PPAR- γ Properties and Risk Assessment
16 Amorfrutin 3Weidner et al., 2012PPAR- γ Properties and Risk Assessment
17 Amorfrutin 4Weidner et al., 2012PPAR- γ Properties and Risk Assessment
18 SwertiamarinPatel et al., 2013PPAR- γ Properties and Risk Assessment
19 GentianineVaidya et al., 2012PPAR- γ Properties and Risk Assessment
20 Dehydrotrametenolic acidSato et al., 2002PPAR- γ Properties and Risk Assessment
21 Gallic acidHuang et al., 2005PPAR- γ Properties and Risk Assessment
22 CarnosolRau et al., 2006PPAR- γ Properties and Risk Assessment
23 Amorfrutin 1Weidner et al., 2012PPAR- γ Properties and Risk Assessment
24 HonokiolKatz et al., 2007PPAR- γ Properties and Risk Assessment
25 Amorfrutin BWeidner et al., 2013PPAR- γ Properties and Risk Assessment
26 3-p-coumaroylquinic acidPitschmann et al., 2014PPAR- γ Properties and Risk Assessment
27 TurmeroneKuroda et al., 2005PPAR- γ Properties and Risk Assessment
28 Lipoic acidChristensen et al., 2010PPAR- γ Properties and Risk Assessment
29 CurcuminKuroda et al., 2005 Nishiyama et al., 2005PPAR- γ Properties and Risk Assessment
30 6-GingerolChakraborty et al., 2012PPAR- γ Properties and Risk Assessment
31 DemethoxycurcuminKuroda et al., 2005PPAR- γ Properties and Risk Assessment
32 BisdemethoxycurcuminKuroda et al., 2005 Nishiyama et al., 2005PPAR- γ Properties and Risk Assessment
33 ar-turmeroneKuroda et al., 2005 Nishiyama et al., 2005PPAR- γ Properties and Risk Assessment
34 Cyanidin-3-glucosideMatsukawa et al., 2015PPAR- γ Properties and Risk Assessment
35 CitronellolKatsukawa et al., 2011PPAR- γ Properties and Risk Assessment
36 3-Caffeoylquinic AcidZhang et al., 2013PPAR- γ Properties and Risk Assessment